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On Edge Performance

FOCUS (EAGLE 1)

FOCUS (EAGLE 1)

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On Edge Performance FOCUS (EAGLE 1)  helps by improving mental clarity and focus, boosting intelligence levels and memory function, and increasing your level of concentration and alertness. As a bonus, FOCUS (EAGLE 1) can provide you with an increased level of energy and improved mood.*

Formula Purposes & Benefits
FOCUS (EAGLE 1) is formulated to boost cognitive function, mental clarity, focus, immune function, and energy production.
Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients.
Our formula is third-party independently tested for heavy metals and impurities, made in the USA, GMP certified, and produced in an FDA-registered facility. 1% of the supplements on the market can match our world-class standards.

 

Formula Ingredient Deck Benefits Of Each Ingredient 
Vitamin A
  • It supports vision, skin, and immune health while also enhancing antioxidant support (182, 183).
    Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased L-glutathione production (master antioxidant) (182,183).
  • Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182,183).
Vitamin C
  • Supports immune, cardiovascular, skin, cognitive, fat-burning, and digestive health (97, 98).
  • Supports immune health by increasing oxidant and free radical scavenging, as well as fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98).
  • Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98).
  • Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98).
Vitamin D
  • It supports exercise performance, immune health, muscle growth, optimal bone health, hormonal health, immune function, increased sexual health, cardiovascular health, glucose tolerance, strength, and positive mood (77,78,79).
  • Supports hormonal health through high levels of vitamin D receptor (VDR) activity in hormone-based feedback loop reactions (77,78).
  • Supports cardiovascular health through improved calcium absorption, reduced atherosclerotic activity, stimulation of cardiomyocytes, and enhanced vascular health (77,78).
  • Supports exercise performance via reduced exercise-associated inflammation and muscle damage (77,78).
  • Supports sexual health via increased activity of Vitamin D receptors and testosterone production (79).
  • It supports immune function by decreasing inflammatory cytokines and enhancing the function of immune cells (77,78).
  • Supports joint health by regulating calcium and phosphorus levels and promoting bone remodeling, along with other calcium-regulating actions (77,78).
Vitamin E
  • Supports immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208)
  • It supports immune health via neutralizing free radicals and reactive oxygen species and increases T lymphocyte-mediated immune function (204).
  • Supports cardiovascular health by reducing cholesterol levels (204).
  • Supports cognitive function by reducing oxidative stress, inflammation, and DNA damage in neuronal tissues (208).
Vitamin B1 (Thiamine)
  • It supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94).
  • It supports cardiovascular function and acts as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95).
Vitamin B2 (Riboflavin)
  • It supports conversion and activation of other B vitamins and red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93).
Vitamin B3 (Niacin)
  • A significant B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9).
  • Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9).
  • Vital for regulation of gene expression, cell cycle progression, DNA repair, and cell death (9).
  • Supports a healthy inflammatory response through its antioxidant and anti-apoptotic (prevention of cell death) properties (9).
  • It prevents pathologies(diseases) such as Crohn's disease and reduces the prevalence of nervous anorexia, cancer, and Crohn's disease (10, 11).
  • Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12).
  • Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid, and reducing neuroinflammation (9).
  • Increased niacin-associated NAD+ levels have been shown to enhance neurotransmission, learning, and memory (9).
  • Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9).
Vitamin B6
  • It serves as a cofactor in more than 150 enzymatic reactions associated with blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic and digestive health (38, 40).
  • Reduces plasma glucose (blood sugar levels) by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39).
  • It functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40).
  • May support blood sugar regulation in women with gestational diabetes (40).
  • Cofactor for enzymes involved in DNA metabolism (40).
Folic Acid
  • It may support proper cell growth and DNA synthesis (65).
Biotin
  • Supports the conversion of food into cellular energy, as well as hair and skin health, and cognitive function (213, 214).
  • Enhances glucose breakdown into skeletal muscle tissue (213,214).
Vitamin B5
  • It supports energy production, cell growth, cell repair, cognitive function, increased hippocampal volume (enhancing memory), and optimized bioenergetics (the burning of carbohydrates, fat, and protein) (96).
Calcium
  • Supports bone health, muscle function, and cardiovascular health (36,37).
  • Regulates processes of bone resorption, mineralization, and fracture repair (36,37).
  • Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37).
  • Prevents the development of preeclampsia (36,37).
Iron
  • It supports red blood cell formation, immune function, and antioxidant support (215,216).
  • May increase oxygen uptake into red blood cells of iron-deficient individuals (215,216).
  • It may support the gut health of individuals with iron deficiency.
  • Combats anemia in iron-deficient individuals (217).
Magnesium
  • Supports optimal nerve function, muscle contractions, cardiovascular health, and bone health, and reduces anxiety (90, 91).
  • It supports biological reactions, such as ATP-fueled reactions and pancreatic insulin secretion (90, 91).
  • Supports the reduction of systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91).
  • Reduces peripheral cortisol levels in the central nervous system (CNS) and supports relaxation and decreased anxiety (90,91).
Zinc
  • Supports immune function, skin health, cognitive function, and vision (172,173).
  • Supports the stimulation of both the innate and adaptive immune systems (172,173).
  • Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173).
  • Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173).
Selenium
  • Supports antioxidant function, cardiovascular health, cognitive function, thyroid health, and immune health (145, 146).
  • Combats atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147).
  • Supports thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146).
  • Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increase natural killer activity, and increase glutathione (master antioxidant) levels (145,147).
Copper
  • Supports healthy blood sugar levels, energy metabolism, and cholesterol management (143,144).
Manganese
  • It supports enzymatic antioxidant reactions, increases bone mineral density, and regulates blood sugar levels (148,149).
Chromium
  • It supports insulin function, reduces cholesterol, improves blood sugar regulation, and may lower cholesterol (218,219).
Molybdenum
  • Increases enzymatic reactions involved in sulfite metabolism and detoxification (150).
DMAE Bitartrate
  • Increases acetylcholine levels in the brain.
L-Glutamine
  • The most abundant amino acid in skeletal muscle fuels immune cells, improves exercise recovery, and optimizes the gut microbiome (18).
  • Vital for lymphocyte (immune cell) proliferation (growth) and paramount in neutrophil (immune cell) destruction of bacteria (18).
  • Vital for activation of genetic signals that support immune function and vitality (18).
  • Glutamine is utilized by immune cells at high rates during catabolic conditions (post-surgery, sepsis, burns, and extreme exercise (18).
Glutamic Acid
  • Supports cognitive function and focus (220).
Green Tea Extract
  • A potent polyphenolic antioxidant that supports blood pressure, insulin sensitivity, and metabolic health (26).
  • High in ECGC (epigallocatechin gallate) (26).
  • ECGC is shown to reduce body fat mass, increase fat oxidation(burning), and increase caloric expenditure during exercise (25).
  • Potent anti-inflammatory compound supporting glutathione production and inhibition of pro-inflammatory markers (cytokines) (26).
  • Reduces oxidative stress (chronic inflammation in the body) (26).
Choline
  • Essential for cell membrane integrity, cell messaging, fat metabolism, DNA synthesis, immune support, and nervous system function (62,63).
  • It serves as a methyl donor and as a precursor for the production of cell membranes (62).
  • Precursor for acetylcholine (neurotransmitter), which activates receptors in the central nervous system-mediated immune responses (α7nAchR) (64).
  • Lifelong choline supplementation may combat neurodegenerative diseases by reducing amyloid-β plaque load (plaques of degrading neurons) (62).
  • Reduces the concentration of total homocysteine (inflammation marker) in individuals with low levels of folate and other B vitamins (B₂, B₆, and B₁₂) (62).
Inositol
  • It supports liver detoxification, combats metabolic syndrome, and acts as an antioxidant (221).
  • Combats metabolic syndrome via reduced levels of triglycerides, total- and LDL-cholesterol (221).
  • Supports antioxidant function via reduced levels of reactive oxygen species and inflammatory markers (interleukin 6) (222).
N-Acetyl Tyrosine
  • It supports memory, cognitive flexibility, the executive function of the brain, and convergent thinking (60).
  • The precursor to dopamine is vital for dopamine synthesis in the brain (60).
  • Supports cognitive function in individuals with high amounts of stress and anxiety (60,61).
  • Increases dopamine levels in highly stressed individuals (60).
Bilberry Fruit
  • It supports vision health, cardiovascular function, increased nitric oxide production, and antioxidant support (223,224).
Grape Seed Extract
  • It supports increased nitric oxide production, reduces blood pressure, mitigates DNA damage, stimulates collagen production, enhances bone strength, and acts as a neuroprotective agent (31).
  • Supports antioxidant function through modulation of antioxidant enzyme expression, protection against oxidative damage, and reduction of reactive oxygen species (31).
  • Supports cardiovascular health by reducing atherosclerosis, inhibiting lipid peroxidation, and improving endothelial vascular function (31).
Olive Leaf
  • Supports cardiovascular health, antioxidant function, and controlled blood sugar levels (224).
  • Supports Cardiovascular health via reduction of systolic BP, LDL, and inflammatory biomarkers (224).
  • It supports antioxidant function via anti-inflammatory polyphenols that protect against DNA damage initiated by free radicals (225).
  • Combats major inflammatory pathways via anti-inflammatory change involving the inflammation pathway (NF-κB inhibition) (225).
  • Supports blood sugar regulation via improved insulin sensitivity and pancreatic β-cell (cells responsible for secreting insulin) secretory capacity (226).
Licorice Root
  • It supports anti-inflammatory, anti-allergenic, and antimicrobial properties (177).
Boron
  • Supports increased bone mineral density, muscle function, hormonal balance, and immune function (180).
DHA (Fish Oil)
  • Vital for optimal cardiovascular, hormonal, immune, cognitive, digestive health, and recovery from exercise (73,74,76).
  • Consuming 6 grams of fish oil per day has been shown to reduce inflammation, alleviate muscle soreness, and decrease the perception of pain in exercising individuals (76).
  • Increases skeletal muscle hypertrophy than individuals consuming only whey protein post-exercise (76).
  • Supports cardiovascular health by reducing atrial fibrillation, atherosclerosis (plaque buildup), thrombosis, and blood pressure, while also supporting blood lipid profiles (cholesterol panel) (73,74,75).
  • Lowers blood pressure via increased nitric oxide production and induces endothelial relaxation (75).
  • Supports healthy information by decreasing C-reactive protein (an inflammatory marker) in the body and increasing insulin sensitivity (75, 76).
  • It supports cognitive health by increasing the concentration of omega-3 fatty acids in the cell membranes of the cerebral cortex and synaptic vesicles (76).
Vanadyl Sulfate
  • Supports blood sugar regulation via improved insulin sensitivity and pancreatic beta-cell function (cells that produce insulin) (227).
Phosphatidylserine
  • Supports cognitive function, memory, and focus while also reducing stress (228,229).
  • Reduces the prevalence of short-term memory loss in patients with ADHD, improving the function of pyramidal cells in the prefrontal cortex (PFC) (228).
  • Increases dopamine and acetylcholine release via maintenance of acetylcholine supply (228).
  • Reduces cortisol levels in the frontal brain regions during stressful activity (228,229).
Huperzine A
  • It supports cognitive function, memory, and focus and helps combat neurodegenerative diseases (230).
  • Combats neurodegenerative disease via improvement of cognitive function, dailAlzheimer's activities, and global clinical assessment in participants with Alzheimer’s disease (230).
Proper Use of This Supplement
Suggested Use: As a dietary supplement, take two (2) veggie capsules daily. For best results, take 20-30 minutes before a meal with an 8-oz glass of water, or as directed by your healthcare professional.

 

Our Formula Vs.Other Formulas on the Market.
1. Uses third-party, independently tested ingredients that are made in the USA, GMP certified, and made in an FDA-registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements that are not third-party tested have been removed by the FDA due to high levels of heavy metals.
2. Uses high-quality nutraceuticals in a practical, evidence-based, and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers and heavy metals and are formulated without evidence-based dosages.

Sources

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  2. Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research83, 151–194. https://doi.org/10.1016/bs.afnr.2017.11.004
  3. Bailey, L. B., Stover, P. J., McNulty, H., Fenech, M. F., Gregory, J. F., 3rd, Mills, J. L., Pfeiffer, C. M., Fazili, Z., Zhang, M., Ueland, P. M., Molloy, A. M., Caudill, M. A., Shane, B., Berry, R. J., Bailey, R. L., Hausman, D. B., Raghavan, R., & Raiten, D.Journal15). Biomarkers of Nutrition for Development-Folate Review. The Journal of Nutrition145(7), 1636S–1680S. https://doi.org/10.3945/jn.114.206599
  4. Thakur, K., Tomar, S.K., Singh, A.K., Mandal, S., & Arora, S. (2017). Riboflavin and health: A review of recent human research. Critical reviews in food science and nutrition, 57(17), 3650–3660. https://doi.org/10.1080/10408398.2016.1145104
  5. Suwannasom, N., Kao, I., Pruß, A., Georgieva, R., & Bäumler, H. (2020). Riboflavin Journal: Health Benefits of a Forgotten Natural Vitamin. International journal of molecular sciences, 21(3), 950. https://doi.org/10.3390/ijms21030950
  6. DiNicolantonio, J. J., Niazi, A. K., Lavie, C. J., O'Keefe, J. H., & Ventura, H. O. (2013). Thiamine supplementation for the treatment of heart failure: a review of the literature. Congestive heart failure (Greenwich, Conn.), 19(4), 214–222. https://doi.org/10.1111/chf.12037
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  9. DePhillipo, N. N., Aman, Z. S., Kennedy, M. I., Begley, J. P., Moatshe, G., & LaPrade, R. F. (2018). Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress after Musculoskeletal Injuries: A Systematic Review. Orthopedic journal of sports medicine, 6(10), 2325967118804544. https://doi.org/10.1177/2325967118804544
  10. Eggersdorfer, M., & Wyss, A. (2018). Carotenoids in human nutrition and health. Archives of biochemistry and biophysics, 652, 18–26. https://doi.org/10.1016/j.abb.2018.06.001
  11. Sunkara, A., & Raizner, A. (2019). Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment. Methodist DeBakey Cardiovascular Journal, 15(3), 179–184. https://doi.org/10.14797/mdcj-15-3-179
  12. Age-Related Eye Disease Study Research Group (2001). A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Archives of ophthalmology (Chicago, Ill.: 1960), 119(10), 1417–1436. https://doi.org/10.1001/archopht.119.10.1417
  13. Jovic, T. H., Ali, S. R., Ibrahim, N., Jessop, Z. M., Tarassoli, S. P., Dobbs, T. D., Holford, P., Thornton, C. A., & Whitaker, I. S. (2020). Could Vitamins Help in the Fight Against COVID-19? Nutrients, 12(9), 2550. https://doi.org/10.3390/nu12092550
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  15. Wu, D., & Meydani, S. N. (2014). Age-Associated Changes in Immune Function: The Impact of Vitamin E Intervention and Its Underlying Mechanisms. Endocrine, metabolic & immune disorders drug targets, 14(4), 283–289. https://doi.org/10.2174/1871530314666140922143950
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  20. Cappellini, M. D., Musallam, K. M., & Taher, A. T. (2020). Iron deficiency anemia revisited. Journal of Internal Medicine, 287(2), 153–170. https://doi.org/10.1111/joim.13004
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* The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.

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